For the coat in the spring, 1/4 pound of braces? of Antimony, 1/4 pound of cream of tartar, 1/4 pound of whites, 1/4 pound of sulphur. (For a stallion); half the quantity for common horse.

James’s Powder was formerly a patent medicine, in which antimony was the most important ingredient.

Antimony for medical use has a history stretching back to ancient times. But the use of such a potentially toxic purgative has provoked bitter disagreement among practitioners, and despatched countless men and women to an early grave.  Advanced by some early modern healers as a near miraculous panacea, it was also revered by alchemists because of its uncanny power to purify gold. By 1678, over 106 standard remedies contained antimonials of various sorts; even more could be found in any 19th century medicine chest.

An Antimony pill is made from metallic antimony. It was a popular remedy in the nineteenth century, and it was used to purge and revitalise the bowels. In use, it is swallowed and allowed to pass through the body, after which it is customarily recovered for reuse, giving rise to the name everlasting pill.

According to the Medico-Pharmaceutical Critic and Guide (1907), edited by William J. Robinson:

We have referred in the past to the economy which used to be practiced by our fore-fathers. Thus, for instance, it was customary to use leeches over and over again and there are instances of infection with syphilis by leeches that had been previously used on luetic patients. But we believe that the everlasting cathartic pill beats everything in the line of economy. This pill was a little bullet composed of metallic antimony which had or was believed to have the property of purging as often as it was swallowed. It is not inconceivable that it might have had such property, for it is possible that a minute amount was dissolved by the gastro-intestinal juices and this amount, plus the suggestion, was sufficient to produce cathartic action. Then again the everlasting pill probably aided peristalsis by its mechanical weight and motion. The bullet was passed out, recovered from the feces and used over and over again. This, as Dr. J. A. Paris says, was economy in right earnest, for a single pill would serve a whole family during their lives and might be transmitted as an heirloom to posterity.

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